Two strangers are drawn to a mysterious pharmaceutical trial for a drug that they're assured will, with no complications or side-effects whatsoever, permanently solve all of their problems. Things do not go as planned.
Episodes
Season 1 - Episodes
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S01E01The Chosen One!
Aired: 21 Sep. 2018
Show details expand_moreDiagnosed with schizophrenia, Owen is the black sheep of the wealthy Milgrim clan. After losing his job, he enrolls in an experimental drug trial.
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Cary Joji Fukunaga, Danielle Henderson
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Cary Joji Fukunaga, Danielle Henderson
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S01E02Windmills
Aired: 21 Sep. 2018
Show details expand_moreWhen her pilfered stash of pills runs out, troubled Annie tries to quit -- but ends up blackmailing her way into the Neberdine study.
Stars: Jonah Hill, Emma Stone, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Cary Joji Fukunaga, Danielle Henderson
Stars: Jonah Hill, Emma Stone, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Cary Joji Fukunaga, Danielle Henderson
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S01E03Having a Day
Aired: 21 Sep. 2018
Show details expand_moreMuramoto notices irregularities in Annie and Owen's data. He questions Owen, who recalls the worst night of his life: his brother's engagement party.
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Caroline Williams, Cary Joji Fukunaga
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Caroline Williams, Cary Joji Fukunaga
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S01E04Furs by Sebastian
Aired: 21 Sep. 2018
Show details expand_moreAfter taking the B pill, Annie and Owen find themselves on 1980s Long Island entangled in a strange caper involving a lemur.
Stars: Jonah Hill, Emma Stone, Sonoya Mizuno
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Nick Cuse, Cary Joji Fukunaga
Stars: Jonah Hill, Emma Stone, Sonoya Mizuno
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Nick Cuse, Cary Joji Fukunaga
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S01E05Exactly Like You
Aired: 21 Sep. 2018
Show details expand_moreAnnie and Owen are Arlie and Ollie, grifters attending a séance at the mysterious Neberdine mansion in the 1940s.
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Caroline Williams, Mauricio Katz, Patrick Somerville
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Caroline Williams, Mauricio Katz, Patrick Somerville
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S01E06Larger Structural Issues
Aired: 21 Sep. 2018
Show details expand_moreAzumi tells James the whole truth about the study's snags and urges him to call his estranged mother, an esteemed therapist.
Stars: Jonah Hill, Emma Stone, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Nick Cuse, Cary Joji Fukunaga
Stars: Jonah Hill, Emma Stone, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Nick Cuse, Cary Joji Fukunaga
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S01E07Ceci N'est Pas Une Drill
Aired: 21 Sep. 2018
Show details expand_moreOwen and Annie take the C pill. No longer connected, he belongs to a Mafia family, and she's a medieval guide hired by an ailing elf princess.
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Amelia Gray, Danielle Henderson, Patrick Somerville
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Amelia Gray, Danielle Henderson, Patrick Somerville
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S01E08The Lake of the Clouds
Aired: 21 Sep. 2018
Show details expand_moreAnnia and Ellia continue their quest, and Owen's mafioso father pressures him to protect the family. Greta counsels a bereaved Gertie.
Stars: Jonah Hill, Emma Stone, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Mauricio Katz, Nick Cuse, Patrick Somerville
Stars: Jonah Hill, Emma Stone, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Mauricio Katz, Nick Cuse, Patrick Somerville
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S01E09Utangatta
Aired: 21 Sep. 2018
Show details expand_moreOwen and Annie meet again as a disgraced Icelandic spy and a CIA operative who helps him. Greta implores James to shut down the trial.
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Cary Joji Fukunaga, Danielle Henderson
Stars: Emma Stone, Jonah Hill, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Cary Joji Fukunaga, Danielle Henderson
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S01E10Option C
Aired: 21 Sep. 2018
Show details expand_moreAfter the subjects are discharged, James and Azumi face Neberdine's CEO. Owen and Annie part ways -- until a startling headline sparks a reunion.
Stars: Jonah Hill, Emma Stone, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Cary Joji Fukunaga, Danielle Henderson
Stars: Jonah Hill, Emma Stone, Justin Theroux
Director(s): Cary Joji Fukunaga
Writer(s): Patrick Somerville, Cary Joji Fukunaga, Danielle Henderson